NFL Week 18 Anytime TD Scorers: 49ers vs. Cardinals (2025)
Things started so well last week. My first two Anytime Touchdown (ATD) and First Touchdown (FTD) picks netted five total touchdowns, including a first touchdown. But things got away from us a bit after that. The total hit was only about 0.7 units. Hopefully, that was just a bump in the road. Below are my picks for all 13 games on the Sunday slate, excluding the showdown on Sunday night between Detroit and Minnesota.
This week is going to be tricky when it comes to anytime touchdown and first touchdown picks. Many players have question marks surrounding their workloads. Because of this, sportsbooks have not listed anytime touchdown and first touchdown pricing for multiple games. With so much up in the air, touchdown prices can move quickly. I am authoring this week’s article as late as possible to mitigate some of the movement. But nothing is set in stone. If I like a player at even money, that does not necessarily mean I will like him at -180. As always, use your discretion and bet responsibly.
As a reminder, I am tracking these using bet sizes of 0.4 units on anytime touchdown bets and 0.1 units on first touchdown bets. Whether you play one or all, use your discretion and adjust as you see fit. We compare anytime touchdown stats to prop bet odds and projections to help identify this week’s best bets. Here are our top NFL Week 18 anytime and first touchdown scorers. Below are our favorite NFL TD scorers for 49ers vs. Cardinals.
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Best NFL Week 18 Anytime TD Scorer Prop Bets: 49ers vs. Cardinals
All wagers are 0.5 units
NFL Anytime Touchdown Scorer Prop Bets
Who will score a touchdown in this week’s NFL Games? The Anytime TD market covers any player who carries or receives the ball into the end zone, not the quarterback who passes the ball. We compare anytime touchdown stats to prop bet odds and projections to help identify today’s best bets. View Anytime Touchdown odds across sportsbooks here.
49ers vs. Cardinals
- Anytime TD Odds: +150 at DraftKings Sportsbook
- First TD Odds: +850 at DraftKings Sportsbook
The San Francisco 49ers and Arizona Cardinals have combined to allow nine rushing touchdowns to opposing quarterbacks. Based on that, I do not mind going with Kyler Murray or Joshua Dobbs to rush for a score. However, 49ers’running back Isaac Guerendo is a solid value this week. Guerendo has been the primary ball-carrier for San Francisco in his last three games. He scored twice in those three games while averaging over 100 scrimmage yards.
The Cardinals have allowed the third-most rushing yards and second-most touchdowns to opposing backs over the last four weeks. While the 49ers abandoned the run against the potent Detroit Lions, that should not be the case this week with Dobbs under center against a less explosive opponent. I like Guerendo at plus-money to find the end zone in Week 18.